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Participants in TRAILBLAZER-ALZ 2 were stratified by their level of tau, a predictive biomarker for disease progression, into either a low-medium tau group (sometimes referred to as intermediate tau) or a high tau group, which represented a later pathological stage of disease. TRAILBLAZER-ALZ 2 results, see the publication in JAMA. This is the first Phase 3 study of a disease-modifying therapy to replicate the positive clinical results observed in a previous study said Anne White, executive vice president of Avid Radiopharmaceuticals.

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