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XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring. Ischemic Heart Disease: In the combined data of four randomized, placebo-controlled clinical studies, ischemic heart disease occurred more commonly in patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC). TALZENNA is first and only PARP inhibitor approved for use in men with metastatic generic Pepcid 20 mg from Pittsburgh castration-resistant prostate cancer (mCRPC).
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