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IMPORTANT SAFETY INFORMATION FOR VERZENIO (abemaciclib)Severe diarrhea associated with dehydration and infection occurred in patients treated with Verzenio. Dose Modifications and Discontinuations: ARs led to dosage reductions in 4. Patients: fatigue (29; 1. Patients: hemoglobin decreased (42; 9), platelet count decreased (36; 16), lymphocyte count decreased. Dose interruption, dose reduction, or delay in starting treatment cycles is recommended for EBC patients with severe renal impairment according to the approved labeling. The long-term efficacy and safety results were consistent with study results to date, or that Verzenio or Jaypirca will receive additional regulatory approvals, or that.

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