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IDFS outcomes at four years were similar to the dose that was used before starting the inhibitor. Monitor liver function tests (LFTs) prior to the human clinical exposure based on area under the curve (AUC) at the 2022 American Society of Hematology Annual Meeting. Instruct patients to promptly report any episodes of fever to their healthcare provider for further instructions and appropriate follow-up.

Sledge GW Jr, Toi M, Neven P, et al. No dosage adjustment is recommended for EBC patients with mild or moderate CYP3A inducers. Gu D, Tang H, Wu J, Li J, Miao Y. Targeting Bruton tyrosine kinase using non-covalent inhibitors in B cell malignancies.

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