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It is most commonly observed as temporary swelling in an area or areas of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. To learn more, visit Lilly. The overall treatment effect of donanemab continued to grow throughout the trial, with the largest differences versus placebo seen at 18 months. For full TRAILBLAZER-ALZ 2 results, see the publication in JAMA.
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That includes delivering innovative clinical trials that reflect the diversity of our world and working to ensure our medicines are accessible and affordable.