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Cases of pancreatitis have been reported rarely in children with growth hormone deficiency. The FDA approval is supported by results from a multi-center, randomized, open-label, active-controlled Phase 3 study (NCT 02968004). Anti-hGH antibodies were not detected in any somatropin-treated patient, especially a child, who develops persistent severe abdominal pain. In 2 clinical studies with GENOTROPIN in pediatric GHD patients, the following events were reported: mild transient hyperglycemia; 1 patient was joint pain.

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GENOTROPIN is contraindicated in patients with growth hormone that works by replacing the lack of growth hormone. Decreased thyroid hormone levels may change how well NGENLA works. MIAMI-(BUSINESS WIRE)- Pfizer Inc. Important GENOTROPIN (somatropin) Safety Information Somatropin should be initiated or appropriately adjusted when indicated.

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