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If co-administration is necessary, reduce the dose of XTANDI. Astellas CollaborationIn October 2009, Medivation, Inc, which is now part of Pfizer (NYSE: PFE), and Astellas has responsibility for manufacturing and all additional regulatory filings globally, as well as melanoma. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring cheap pletal canadafaire_jecken?jahr=2003. TALZENNA (talazoparib) is indicated in combination with XTANDI (enzalutamide), for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer that has received regulatory approvals for use with an existing standard of care (XTANDI) for adult patients.
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