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The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions and anaphylaxis were also observed. This delay in progression meant that, on average, participants treated with donanemab had an additional 7. CDR-SB compared to those on placebo. Donanemab specifically targets deposited amyloid plaque and has how to buy rebetol online been shown to lead to plaque clearance in treated patients.

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It is most commonly observed as temporary swelling in an area or areas of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. The overall treatment effect of donanemab continued to grow throughout the trial, with the largest differences versus placebo seen at 18 months. Serious infusion-related how to buy rebetol online reactions and anaphylaxis were also observed.

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