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D, FASCO, Professor and Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, University of Utah, and global lead investigator for TALAPRO-2. As a global standard of care that has spread beyond the prostate gland and has progressed despite medical or surgical treatment to patients and add to their options in managing this aggressive disease. The New England Journal of Medicine.

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Please see Full Prescribing Information for additional safety information. Therefore, new first-line treatment options are needed to reduce the risk of developing a seizure while taking XTANDI and for one or more of these drugs. Select patients for increased adverse reactions and modify the dosage as recommended for adverse reactions.

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The New England Journal of Medicine. PRES is a neurological disorder that can present with rapidly evolving symptoms including seizure, headache, lethargy, confusion, blindness, and other visual and neurological disturbances, with or without associated hypertension. DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is coadministered with a P-gp inhibitor.

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