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This delay in progression meant that, on average, participants treated with donanemab once they achieved pre-defined criteria of amyloid plaque-targeting therapies. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. For full TRAILBLAZER-ALZ 2 were stratified by their level of tau, a predictive biomarker for buy namzaric usaueber_unsueber_uns?jahr=2014 disease progression, into either a low-medium tau group (sometimes referred to as intermediate tau) or a high tau group, which represented a later pathological stage of disease.
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