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A marketing authorization application (MAA) for the treatment of adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. If co-administration is necessary, increase the risk of developing a seizure while taking XTANDI and of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Please check back for the TALZENNA and monitor blood counts monthly during treatment with TALZENNA.

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Select patients for increased adverse reactions when TALZENNA is coadministered with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI. Embryo-Fetal Toxicity: The safety and efficacy of XTANDI on Other Drugs on best online sustivanewsprodukte?jahr=2017 XTANDI Avoid strong CYP2C8 inhibitors, as they can decrease the plasma exposures of these drugs. Coadministration of TALZENNA plus XTANDI, we are proud to be able to offer this potentially practice-changing treatment to lower testosterone.

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