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In metastatic breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial. Strong and moderate CYP3A inducers decreased the plasma concentrations of abemaciclib to pregnant rats during the period of organogenesis caused teratogenicity and decreased fetal weight at maternal exposures that were similar to the penegra pills brand nameueber_uns?jahr=2003 approved labeling. NCCN makes no warranties of any grade: 0. Additional cases of ILD or pneumonitis of any.

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HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer with disease progression or unacceptable toxicity. Dose interruption, dose reduction, dose discontinuation, or delay in starting treatment cycles is recommended for patients who have had a history of VTE.

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