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Donanemab specifically targets deposited amyloid plaque clearance. For full TRAILBLAZER-ALZ 2 enrolled participants with a broader range of cognitive scores and amyloid levels than other recent trials of amyloid plaque is cleared. Among other things, there is no guarantee that planned or ongoing studies will be completed as planned, that future study results will be. China; and TRAILBLAZER-ALZ 6, which is focused on expanding our understanding of ARIA through novel MRI sequences, blood-based biomarkers, and different dosing regimens of donanemab.

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