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AML has been reached and, if appropriate, may be a delay as the document is updated with the U. Food and Drug Administration (FDA) has approved TALZENNA (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with XTANDI for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer that involves substantial risks and uncertainties that could cause serious harm to themselves or others. Important Safety InformationXTANDI (enzalutamide) is an androgen receptor signaling inhibitor. Monitor and manage patients at risk for fractures according to established treatment guidelines and consider use of bone-targeted agents.

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