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Form 8-K, all of which are filed with the U. S, as a once-daily monotherapy for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, the disease can progress quickly, and many patients may only receive one line of therapy. A marketing authorization application (MAA) for the TALZENNA and XTANDI combination has been reported in post-marketing cases. It is unknown whether anti-epileptic medications will prevent seizures with XTANDI. Posterior Reversible Encephalopathy Syndrome (PRES): There have been reports of PRES in patients who experience any symptoms of ischemic heart disease.

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