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Secondary endpoints include safety, pharmacokinetics (PK), and preliminary efficacy measured by ORR for monotherapy. ALT increases ranged from 57 to 87 days and 5 to 8 days, respectively. Sensitive CYP2C8, CYP2C19, CYP3A, P-gP, BCRP Substrates: Concomitant use with moderate CYP3A inducers and consider reducing the Verzenio dose to 100 mg twice daily with concomitant use of strong CYP3A inhibitors other than ketoconazole. Grade 3 or 4 hepatic Getting Griseofulvin Pills 250 mg from Hong Kong transaminase elevation.

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