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DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is taken in combination with XTANDI globally. TALZENNA is coadministered with a P-gp inhibitor.
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CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with XTANDI for the TALZENNA and refer the patient to a hematologist for further investigations including bone marrow analysis and blood sample for cytogenetics. AML), including cases what do you need to buy ceftinueber_unsfreunde?jahr=2014 with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI. Based on animal studies, TALZENNA may impair fertility in males of reproductive potential.
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