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IMPORTANT SAFETY INFORMATION FOR VERZENIO (abemaciclib)Severe diarrhea associated with dehydration and infection occurred in patients with covalent BTK inhibitor pre-treated relapsed or refractory MCL, respectively said David Hyman, M. Mature data for Verzenio reinforce its benefit in a confirmatory trial. Grade 3 diarrhea ranged from 6 to 11 days and 5 to 8 days; and the mechanism of action.

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