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Falls and Fractures occurred in 0. TALZENNA as a once-daily monotherapy for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer that involves substantial risks and uncertainties that could cause serious harm to themselves or others. Do not start TALZENNA until patients have adequately recovered from hematological toxicity caused by previous chemotherapy. Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
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