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You should not take this medication if you are allergic to zolmitriptan, or if you have:

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a history of heart disease, heart attack, or stroke, including "mini-stroke";
severe or uncontrolled high blood pressure;
ischemic bowel disease; or
a headache that seems different from your usual migraine headaches.

Do not use zolmitriptan if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days.

To make sure you can safely take zolmitriptan, tell your doctor if you have any of these other conditions:

liver disease;
kidney disease;
high blood pressure, a heart rhythm disorder; or
coronary heart disease (or risk factors such as diabetes, menopause, smoking, being overweight, having high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. It is not known whether zolmitriptan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Zolmitriptan disintegrating tablets may contain phenylalanine. Talk to your doctor before using this form of zolmitriptan if you have phenylketonuria (PKU). It is not known whether zolmitriptan passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 18 years old.

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