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Angela Hwang, Chief Commercial Officer, President, Global Biopharmaceuticals Business, Pfizer. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell death. No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer.

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