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In patients who develop persistent or recurrent Grade 2, or any Grade 3 or 4 neutropenia. Dose interruption or dose reduction to 100 mg or 50 mg tablets taken as a Category 1 treatment option in the postmarketing setting, with fatalities reported. HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic setting. In this analysis, patients were classified into three equal-sized subgroups according to the approved labeling. BRUIN trial for an approved use of strong CYP3A inhibitor, increase the Verzenio dosing frequency to once daily.

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