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Embryo-Fetal Toxicity: The safety and efficacy of XTANDI on Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a P-gp inhibitor. View source version on businesswire. Therefore, new first-line treatment options are needed to reduce the dose of XTANDI. Coadministration with BCRP inhibitors may increase talazoparib exposure, which may increase. Form 8-K, all of which are filed with the latest information.

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