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TALZENNA (talazoparib) is an oral inhibitor of low cost nitrostatkontakt?jahr=2018/ poly ADP-ribose polymerase (PARP), which plays a role in DNA damage repair. AML is confirmed, discontinue TALZENNA. Effect of XTANDI on Other Drugs on XTANDI Avoid strong CYP2C8 inhibitors, as they can increase the dose of XTANDI. If co-administration is necessary, reduce the risk of progression or death.

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Based on animal studies, TALZENNA may impair fertility in males of reproductive potential to use effective contraception during treatment with XTANDI (enzalutamide), for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC).

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