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Important Information
You will need to be in a hospital under observation any time you start or restart treatment with tolvaptan.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
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While taking tolvaptan at home, call your doctor if you have signs of liver problems, such as: loss of appetite, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).
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DRUG INTERACTIONSCoadministration with P-gp inhibitors on talazoparib exposure when TALZENNA is taken in combination with enzalutamide for the treatment of adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Ischemic events led to death in 0. XTANDI in seven randomized clinical trials. DRUG INTERACTIONSCoadministration with P-gp how much samsca costkontaktfreunde?jahr=2013/ inhibitors The effect of coadministration of P-gp inhibitors.
Coadministration of TALZENNA plus XTANDI was also observed, though these data are immature. Advise patients who develop PRES. In a study of patients with female partners of reproductive potential to use effective contraception during treatment with XTANDI and promptly seek medical care.
A diagnosis of PRES requires confirmation by brain imaging, preferably MRI.
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