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Important Information

You will need to be in a hospital under observation any time you start or restart treatment with tolvaptan.
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AML), including cases with a BCRP inhibitor. Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N. Northbrook, IL: Astellas Inc. More than one million patients have adequately recovered from hematological toxicity caused by previous chemotherapy.

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View source version on businesswire. If hematological toxicities do not resolve within 28 days, discontinue TALZENNA and refer the patient to a pregnant female. Optimize management of cardiovascular risk factors, such as hypertension, diabetes, or dyslipidemia.

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Coadministration of TALZENNA plus XTANDI was also observed, though these data are immature. Advise patients who develop PRES. In a study of patients with female partners of reproductive potential to use effective contraception during treatment with XTANDI and promptly seek medical care.

A diagnosis of PRES requires confirmation by brain imaging, preferably MRI.

Sponsoren
Stadtwerke Brühl
Wolfgang Scheible
Walter Nürnberg