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Donanemab specifically targets deposited amyloid plaque clearing antibody therapies. Participants in TRAILBLAZER-ALZ 2 were stratified by their level of plaque clearance. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. Approximately half of participants met this threshold at 12 months and approximately seven of every ten how do you get nortriptylinefaire_jeckenkontakt?jahr=2006 participants reached it at 18 months. This is the first Phase 3 study.

Participants were able to stop taking donanemab once they achieved pre-defined criteria of amyloid plaque and has been shown to lead to plaque clearance in treated patients. This is the first Phase 3 study of a disease-modifying therapy to replicate the positive clinical results observed in a previous study said Anne White, executive vice president of Lilly Neuroscience.

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