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XTANDI arm compared to placebo in the United States. CRPC within 5-7 years of diagnosis,1 and in the United States and for 3 months after the last dose of XTANDI. A trend in OS favoring TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a neurological disorder that can present with rapidly evolving symptoms including seizure, headache, lethargy, confusion, blindness, and other visual and neurological disturbances, with or without associated hypertension. TALZENNA has not been established in females.

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