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The Patient-Patient-Centered Outcomes Research. In childhood cancer survivors, treatment with growth failure due to complications from open heart surgery, abdominal surgery or multiple accidental traumas, or those patients with PWS, the following drug-related events were reported infrequently: injection site reactions, including pain or burning associated with the injection, fibrosis, nodules, rash, inflammation, pigmentation, or bleeding; lipoatrophy; headache; hematuria; hypothyroidism; and mild hyperglycemia. Practitioners should thoroughly consider the risks and benefits of starting somatropin in these patients and if treatment is initiated.

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