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Monitor patients for signs and symptoms of venous thrombosis and pulmonary embolism and treat appropriately. Atrial Fibrillation and Atrial Flutter: Atrial fibrillation or flutter were reported in 2. Patients with cardiac risk factors such as hypertension or previous arrhythmias may be at increased risk. Neutropenia, including febrile neutropenia and fatal neutropenic sepsis, occurred in 0. Major hemorrhage occurred in. Avoid use of strong CYP3A can coumadin and heparin be given together?jahr=2019 inhibitors. Avoid concomitant use of strong or moderate renal impairment.

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