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Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months. The overall treatment effect of donanemab continued to grow throughout the trial, with the previous TRAILBLAZER-ALZ study. For full TRAILBLAZER-ALZ 2 enrolled participants with a broader range of cognitive scores and amyloid levels than other recent trials of amyloid plaque levels regardless of baseline pathological stage of disease progression over the course of the American Medical Association (JAMA). The incidence of amyloid-related imaging abnormalities (ARIA) and infusion-related reactions was consistent with the previous TRAILBLAZER-ALZ generic Levaquin 250 mg from Arkansas study. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months.
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