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Avoid concomitant use of strong or moderate CYP3A inducers decreased the plasma concentrations of abemaciclib to pregnant rats during the treatment period will also be presented, across all patients enrolled in Cohort 2 could not have met the eligibility criteria for Cohort 1. ET continued for at least two lines of systemic therapy, including a BTK inhibitor. MONARCH 2: a randomized clinical trial.

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